IPC Issues Alert for Meftal: What You Need to Know

The Indian Pharmacopoeia Commission (IPC), a regulatory body for pharmaceutical standards under the Ministry of Health and Family Welfare, has recently issued a drug safety alert concerning the widely used painkiller, mefenamic acid. Often recognized by its popular brand name Meftal, the alert serves as a cautionary measure for healthcare professionals and consumers

Adverse Reactions and Monitoring:
The IPC’s alert emphasizes the importance of close monitoring for potential adverse drug reactions associated with mefenamic acid. It specifically highlights a preliminary analysis revealing the occurrence of eosinophilia and symptoms indicative of the Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome.

Understanding Mefenamic Acid:
Mefenamic acid belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs) and is commonly prescribed for the treatment of mild to moderate pain. Additionally, it finds application in addressing menstrual cramps and other conditions, subject to a doctor’s prescription.

Known Adverse Reactions:
Healthcare professionals stress the significance of patient awareness regarding known adverse reactions, even though they are infrequently observed. Adverse effects such as eosinophilia and the DRESS syndrome, though rare, underscore the need for caution and careful consideration by both medical practitioners and patients.

The Role of IPC:
As an autonomous institution responsible for setting drug standards in India, the IPC regularly updates industry stakeholders on the standards and safety aspects of commonly used drugs. In this instance, their alert aims to prompt vigilance and proactive monitoring in the use of mefenamic acid.

The IPC’s alert serves as a timely reminder for healthcare professionals and consumers alike to exercise diligence in the administration of mefenamic acid. By staying informed about potential adverse reactions and maintaining a cautious approach, both medical practitioners and patients can contribute to safer and more effective healthcare practices. Always consult with a healthcare professional for personalized advice and guidance concerning the use of mefenamic acid or any other prescription medication.

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